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Women’s Pain: Maybe It’s Leptin

What: A study in mice found that female rodents were more likely to release leptin, a hormone associated with heightened pain sensitivity, when signaling pain via “pannexin 1” channels in immune cells. That could be a key to why women feel more pain.

Key line: “Injury to a nerve can be debilitating,” says [y University of Calgary professor Dr. Tuan Trang.] “We know that a lot of preclinical research has been in male subjects. Consequently, treatments were often developed from a male-based understanding and may not be very effective in females.”

Source: University of Calgary

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